Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae . Syringolin A exhibits anti-proliferative activity against a variety of cancer cells ( IC 50 for SK-N-SH, LAN-1, SKOV3 is 20-25 µM), induces apoptosis in SK-N-SH through upregulation of p53 expression and downregulation of Akt/PKB proteins.
Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Akt | Products > Signaling Pathways > Apoptosis
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