Triptriolide inhibits Puromycin aminonucleoside PAN ( HY-15695 )-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3 . Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of TAK1-NF-κB signaling pathway and upregulation of podocin.
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