Terpestacin is found in Phoma exigua var. heteromorpha . Terpestacin binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α . Terpestacin inhibits tumor angiogenesis in the FM3A breast cancer cell xenograft mouse model. Terpestacin has antitumor activity and phytotoxicity.
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