Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that induces vasodilation of precontracted rat aortic strips and endothelium-independent relaxation mechanism. Cimicifugic acid D inhibits extracellular Ca 2+ influx through receptor-operated Ca 2+ channels (ROC) in Norepinephrine ( HY-13715 )-induced contraction of rat aortic strips, without affecting voltage-dependent Ca 2+ channels (VDC) or K + -induced contractions.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calcium Channel
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