Cimicifugic acid A is a cytotoxic caffeic acid derivative that can be isolated from the rhizomes of Cimicifuga heracleifolia . Cimicifugic acid A shows cytotoxic activity against cancer cells, and increases expression of cleaved PARP , thereby exhibiting pro-apoptotic activity. Cimicifugic acid A can be used for colon cancer research.
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