Doliroside A is an Aβ42 -binding agent with an IC 50 of 26.57 μM for Aβ42 . Doliroside A binds to Aβ42 nuclei and oligomers to form stable complexes, suppresses Aβ42 fibrillation, and redirects Aβ42 into off-pathway, amorphous oligomers. Doliroside A can be used for the research of alzheimer’s disease (ad).
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