[8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet ( IC 50 =5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 ( IC 50 =17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 ( IC 50 =5 μM), suppress IKK , Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).
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