Neorauflavane is a tyrosinase inhibitor with mushroom tyrosinase IC 50 values of 30 nM and 500 nM, and K i values of 19 nM and 130 nM. Neorauflavane inhibits monophenolase and diphenolase activities, binds to tyrosinase’s active site via its B-ring resorcinol motif and A-ring methoxy group. Neorauflavane reduces melanin synthesis in melanoma cells. Neorauflavane can be used for the research of skin hyperpigmentation.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Tyrosinase
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