Praeruptorin A

Overview

Praeruptorin A ((+)-Praeruptorin A) is an orally active isomer of (±)-Praeruptorin A ( HY-N0081 ). Praeruptorin A also acts as a Calcium channel blocker. Praeruptorin A can be isolated from Peucedanum . Praeruptorin A serves as a substrate for CYP3A4 . Praeruptorin A downregulates NMDA receptors containing GluN2B and inhibits neuronal Apoptosis . Praeruptorin A mediates vasodilation, inhibits vascular hypertrophy and reduces blood pressure. Praeruptorin A can be used in research related to neurological diseases, myocardial ischemia, heart failure, exertional angina, renovascular hypertension and spontaneous hypertension.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Angina | Products > Disease Areas > Heart Failure | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > iGluR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-N6065
• CAS No.: 73069-27-9
• Molecular Formula: C21H22O7
• Molecular Weight: 386.40
• Purity: 99.57%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.47 mM); Clear solution
• Availability: In-stock

Source

Original product source