4'-Hydroxychalcone

4'-Hydroxychalcone
  • CAS No.:2657-25-2
  • Grade:99.66%
  • Formula:C15H12O2
  • M.W.:224.25
  • Solvent:≥ 2.08 mg/mL (9.28 mM); Clear solution

Overview

4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Oxidative Phosphorylation | Products > Signaling Pathways > Proteasome

Product Information

  • Catalog No.: HY-N7056
  • CAS No.: 2657-25-2
  • Molecular Formula: C15H12O2
  • Molecular Weight: 224.25
  • Purity: 99.66%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (9.28 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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