(-)-Epipodophyllotoxin

(-)-Epipodophyllotoxin
  • CAS No.:4375-07-9
  • Grade:99.95%
  • Formula:C22H22O8
  • M.W.:414.41
  • Solvent:≥ 1.25 mg/mL (3.02 mM); Clear solution

Overview

(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum , with GI 50 s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-N7654
  • CAS No.: 4375-07-9
  • Molecular Formula: C22H22O8
  • Molecular Weight: 414.41
  • Purity: 99.95%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 1.25 mg/mL (3.02 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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