Physalin H

Physalin H
  • CAS No.:70241-09-7
  • Grade:99.98%
  • Formula:C28H31ClO10
  • M.W.:562.99

Overview

Physalin H is a natural product that can be isolated from Solanum nigrum . Physalin H is an inhibitor of Hedgehog ( Hh ) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC 50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC 50 values of 5.7 and 6.8 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > Hedgehog | Products > Signaling Pathways > Endogenous Metabolite

Product Information

  • Catalog No.: HY-N8270
  • CAS No.: 70241-09-7
  • Molecular Formula: C28H31ClO10
  • Molecular Weight: 562.99
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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