5-Iodouracil (Compound 4b) is an irreversible dihydropyrimidine dehydrogenase ( DPD ) inhibitor ( IC 50 =0.22 μM). 5-Iodouracil is promising for research of DPD-overexpressing solid tumors like non-small cell lung cancer (NSCLC).
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Dihydropyrimidine Dehydrogenase (DPD)
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