3-Methyl-L-tyrosine is a derivative of L-Tyrosine ( HY-N0473 ). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine . As a substrate for the protein tyrosine kinase Csk , 3-Methyl-L-tyrosine's relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine , indicating that the methyl modification impacts the processing efficiency of Gsk significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsk 's molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk .
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