Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC 50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine ( HY-12723 )-induced climbing and swimming disruption in mouse models.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor
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