hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a K i of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS ( K i =37 μM) and eNOS ( K i =9.4 μM) is 115-fold and 29-fold, respectively.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > NO Synthase
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