Picolinafen

Overview

Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase ( PDS ) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces ( ROS accumulation, calcium depletion, and activates ( MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis , impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD 50 value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis [1][2] .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-W711035
• CAS No.: 137641-05-5
• Molecular Formula: C19H12F4N2O2
• Molecular Weight: 376.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source