5α-Androstan-3α-ol

Overview

5α-Androstan-3α-ol is a γ-aminobutyric acid ( GABA ) receptor agonist. 5α-Androstan-3α-ol can inhibit the transcriptional activity of the orphan nuclear receptor CAR ( constitutive androstane receptor ). 5α-Androstan-3α-ol negatively regulates the activity of CAR by binding to CAR and promoting its dissociation from coactivator proteins. 5α-Androstan-3α-ol can be used to study nuclear receptor-mediated hormone metabolism and drug detoxification mechanisms.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GABA Receptor | Products > Signaling Pathways > Constitutive Androstane Receptor

Product Information

• Catalog No.: HY-W722556
• CAS No.: 7657-50-3
• Molecular Formula: C19H32O
• Molecular Weight: 276.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source