Carboxy finasteride is a metabolite of the 5α-reductase inhibitor Finasteride ( HY-13635 ). Finasteride is biotransformed by cytochrome P450 ( CYP3A4 ) and is successively oxidized to Hydroxy finasteride and Carboxy finasteride. Carboxy finasteride is the major metabolite in urine, while Hydroxy finasteride is the major metabolite in plasma.
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