ETP-45835

Overview

ETP-45835 is slective and potent MNK inhibitor with IC 50 s of 575 nM and 646 nM for MNK1 and MNK2 , respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MNK

Product Information

• Catalog No.: HY-W846144
• CAS No.: 794510-70-6
• Molecular Formula: C13H16N4
• Molecular Weight: 228.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source