Pipecolic acid is an orally bioavailable, blood-brain barrier-permeable metabolite of lysine with antioxidant , inhibitor, and inducer activity. Pipecolic acid modulates the YAP-GPX4 signaling pathway, reduces retinal vascular tube formation, and mitigates ferroptosis . Pipecolic acid potentiates voltage-sensitive Ca 2+ channel currents and induces neuronal apoptosis . Pipecolic acid can be used for the research of diabetic retinopathy.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > YAP | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis
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