Thioacetamide

Overview

Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model.

Application

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Product Information

• Catalog No.: HY-Y0698
• CAS No.: 62-55-5
• Molecular Formula: C2H5NS
• Molecular Weight: 75.13
• Purity: 98.0%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (33.28 mM); Clear solution
• Availability: In-stock

Source

Original product source