Olcegepant

Overview

Olcegepant is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor, primarily explored for the prevention of migraines in adults. CGRP is a neuropeptide that plays a significant role in migraine pathophysiology, and its receptors are found in the trigeminal ganglion and the central nervous system. By blocking the CGRP receptor, olcegepant aims to prevent the activation of pain pathways associated with migraines. Source summary: Olcegepant is a CGRP receptor antagonist research chemical for biochemical studies; explore properties, handling, and reference data.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | CGRP Receptor

Product Information

• Catalog No.: B0084-441440
• CAS No.: 204697-65-4
• Molecular Formula: C38H47Br2N9O5
• Molecular Weight: 869.65
• Storage: Store at -20 °C
• Solubility: Soluble to ≥ 50 mg/mL in DMSO

Source

Original product source