THZ1

THZ1
  • CAS No.:1604810-83-4
  • Grade:>98%
  • Formula:C31H28ClN7O2
  • M.W.:566.062

Overview

THZ1 is a selective CDK7 inhibitor that preferentially diminishes transcription in cancer cells. THZ1 has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7. Cyclin-dependent kinases (CDKs) are involved in temporal control of the cell cycle and transcription and play central roles in cancer development and metastasis.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | CDK

Product Information

  • Catalog No.: B0084-462601
  • CAS No.: 1604810-83-4
  • Molecular Formula: C31H28ClN7O2
  • Molecular Weight: 566.062
  • Purity: >98%

Source

Original product source


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