(1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | p62 (Sequestosome-1; SQSTM1)
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