Repotrectinib

Overview

TPX-0005 is an orally available and potent ATP-competitive inhibitor of ALK/ROS1/TRK (IC50= 5.3 nM for SRC, IC50= 1.01 nM, 1.26 nM and 1.08 nM for mutant ALKs including WT ALK, ALK G1202R and ALK L1196M, respectively).

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | ALK

Product Information

• Catalog No.: B2693-007261
• CAS No.: 1802220-02-5
• Molecular Formula: C18H18FN5O2
• Molecular Weight: 355.37
• Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
• Solubility: DMSO: ≥ 83.3 mg/mL

Source

Original product source