SAH-SOS1A

Overview

SAH-SOS1A is a cell-permeable, stabilized hydrocarbon-stapled alpha helical peptide that acts as a K-Ras/son of sevenless 1 (SOS1) interaction inhibitor. It binds within nucleotide binding pocket of wild-type and mutant K-Ras. Sequence: RRFFGIXLTNXLKTEEGN (Modifications: Arg-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-7 and X-11 stapled together with a double bond) Source summary: SAH-SOS1A is a specialized peptide used in molecular biology for studies on signaling pathways and cellular functions.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | K-Ras

Product Information

• Catalog No.: B2693-291050
• CAS No.: 1652561-87-9
• Molecular Formula: C100H159N27O28
• Molecular Weight: 2187.53
• Storage: Store at -20°C

Source

Original product source