Galacto-PUGNAc is a selective competitive inhibitor of lysosomal β-hexosaminidases ( HEX ), with K i values of 51 and 18 nM, for hHEXA and hHEXB , respectively. Galacto-PUGNAc elevates GM2 ganglioside levels in neuroblastoma cells. Galacto-PUGNAc can be used for the research of neurodegenerative disorders.
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