SAR113945 monopotassium

Overview

SAR113945 monopotassium is a highly selective IKK-β inhibitor with an IC 50 value of 0.4 nM. SAR113945 monopotassium blocks the canonical NFκB signaling pathway. SAR113945 monopotassium alleviates hyperalgesia to heat and mechanical stimuli, and exerts effects in a zymosan-induced knee joint inflammation model. SAR113945 monopotassium is applicable to research related to symptomatic knee osteoarthritis.

Application

Products | Products > Disease Areas > Pain | Products > Disease Areas > Arthritis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IKK | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-111970B
• CAS No.: 899418-65-6
• Molecular Formula: C28H24KN7O3
• Molecular Weight: 545.63
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source