CDK8-IN-2

Overview

CDK8-IN-2 is an orally active CDK8 inhibitor of an IC 50 values of 0.010 μM. CDK8-IN-2 shows a CDK19 IC 50 value of 0.026 μM. CDK8-IN-2 inhibits phospho- STAT1 , a pharmacodynamic biomarker of CDK8 . CDK8-IN-2 inhibits WNT pathway activity. CDK8-IN-2 can be used for the research of colorectal carcinoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > PASK/STK37 | Products > Signaling Pathways > CDK | Products > Signaling Pathways > STAT

Product Information

• Catalog No.: HY-114178
• CAS No.: 1879980-97-8
• Molecular Formula: C18H17N5O
• Molecular Weight: 319.37
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source