D-Trp-Aib

Overview

D-Trp-Aib is a dipeptide and amyloid-β inhibitor with a K d of 29.6 nM. D-Trp-Aib triggers formation of non-toxic, non-β-sheet, amorphous amyloid β clusters from misfolded amyloid β monomers and toxic amyloid β oligomers, and reduces toxic amyloid β 1-42 deposits. D-Trp-Aib inhibits amyloid fibril formation of α‑synuclein , IAPP and calcitonin . D-Trp-Aib can be used for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > α-synuclein | Products > Signaling Pathways > CGRP Receptor | Products > Signaling Pathways > Amylin Receptor

Product Information

• Catalog No.: HY-114613
• CAS No.: 1123071-24-8
• Molecular Formula: C15H19N3O3
• Molecular Weight: 289.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source