BRD2577 is a selective mercaptopyruvate sulfurtransferase (3-MST) inhibitor with an IC 50 of 9.9 μM. BRD2577 inhibits H 2 S production in colon carcinoma cells. BRD2577 exhibits weak to no significant inhibitory effect on colon cancer cell proliferation and mitochondrial activity. BRD2577 can be used for the research of colon cancer .
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