AZ13581837

Overview

AZ13581837 is an orally active GPR120 agonist with an EC 50 of 5.2 nM for human GPR120. AZ13581837 signals through Gαq , Gαs , and β-arrestin pathways, reduces cAMP production, stimulates GLP-1 secretion, induces glucose lowering, and increases insulin secretion. AZ13581837 can be used for the research of type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 2 Diabetes | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GPR119 | Products > Signaling Pathways > Arrestin | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-115643
• CAS No.: 2896777-27-6
• Molecular Formula: C20H14N2O3S
• Molecular Weight: 362.40
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source