DW532

Overview

DW532 is a dual inhibitor of tubulin and tyrosine kinase , with IC 50 values of 4.9 μM and 5.5 μM against EGFR and VEGFR2 , respectively, and a K D of 3.6 μM for tubulin. DW532 induces cell cycle arrest at the G 2 /M phase, triggers cell apoptosis via caspase-related pathways, and inhibits angiogenesis. DW532 can be used for research related to cancers (e.g., breast cancer ).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Src | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > VEGFR

Product Information

• Catalog No.: HY-116068
• CAS No.: 1267949-42-7
• Molecular Formula: C16H12O6
• Molecular Weight: 300.27
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source