JWU-A021

Overview

JWU-A021 is a GLP-1 secretagogue with an EC 50 of 1.9 μM. JWU-A021 activates the TRPA1 cation channel to promote calcium ion influx and increase intracellular calcium levels in enteroendocrine cells and TRPA1 -transfected cells. By activating the TRPA1 channel, JWU-A021 stimulates the secretion of GLP-1 from intestinal enteroendocrine cells and intestinal L cells. JWU-A021 is applicable to research related to type 2 diabetes.

Application

Products | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GLP Receptor | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-118092
• CAS No.: 1403610-23-0
• Molecular Formula: C16H16ClN
• Molecular Weight: 257.76
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source