Mepyramine hydrochloride

Overview

Mepyramine hydrochloride (Pyrilamine hydrochloride) is a selective histamine H1 receptor antagonist and KCNQ channel inhibitor, with an IC 50 of 12.5 μM against KCNQ2/Q3 . Mepyramine hydrochloride shows no activity against allergic asthma in mice when used alone, but modulates the effect of JNJ 7777120 ( HY-13508 ) on allergic asthma in mice; it inhibits the development of morphine physical dependence and increases histamine levels in mouse brains. Mepyramine hydrochloride can be used in studies related to seizures, convulsions, allergic asthma and morphine physical dependence.

Application

Products | Products > Disease Areas > Allergy | Products > Disease Areas > Epilepsy | Products > Disease Areas > Allergic Asthma | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Histamine Receptor | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-118807A
• CAS No.: 6036-95-9
• Molecular Formula: C17H24ClN3O
• Molecular Weight: 321.84
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source