PIK-124 is a thiazolidinone-based PI3Kγ -biased PI3K inhibitor, with an IC 50 of 3 nM against PI3Kγ . PIK-124 exhibits cross-reactivity with PI3Kα ( IC 50 = 23 nM), PI3Kδ ( IC 50 = 340 nM), PI3KC2α (IC 50 = 140 nM) and PI3KC2β ( IC 50 = 370 nM). PIK-124 is applicable to breast cancer-related research.
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K
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