LG190155

Overview

LG190155 is a nonsteroidal vitamin D receptor ( VDR ) agonist. LG190155 activates VDR in mesenchymal stem cells, thereby upregulating the BMP6-IL6 autocrine axis. Pretreatment of mesenchymal stem cells with LG190155 significantly enhances their ability to induce differentiation of acute myeloid leukemia cells, without inducing hypercalcemia. LG190155 is applicable to research related to acute myeloid leukemia (AML).

Application

Products | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > VD/VDR | Products > Signaling Pathways > TGF-β Receptor | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-118970
• CAS No.: 233268-78-5
• Molecular Formula: C31H44O4
• Molecular Weight: 480.68
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source