NBI 30545

Overview

NBI 30545 is a blood-brain barrier permeable CRF1R antagonist with a K i value of 3.4 nM for the human receptor. NBI 30545 inhibits CRF-stimulated intracellular cAMP accumulation and ACTH release. NBI 30545 can be used in the research of depression, anxiety disorders and stress-related diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Disease Areas > Anxiety or Fear-Related Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > CRFR

Product Information

• Catalog No.: HY-119247
• CAS No.: 195054-99-0
• Molecular Formula: C22H30N4O3
• Molecular Weight: 398.51
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source