KUNG94

Overview

KUNG94 is a selective Grp94/HSP90B inhibitor ( IC 50 =8 nM). By inhibiting the chaperone function of Grp94, KUNG94 reduces the maturation and cell surface trafficking of its specific client proteins. KUNG94 can be used for studies on Grp94-related biological mechanisms, as well as diseases including cancer and primary open-angle glaucoma.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Glaucoma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-119732
• CAS No.: 2134571-29-0
• Molecular Formula: C22H18FNO3
• Molecular Weight: 363.39
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source