PU-20F

Overview

PU-20F is a Hsp90 inhibitor with an EC 50 of 6.8 μM. PU-20F competes with Geldanamycin ( HY-15230 ) for binding to Hsp90 and regulates the function of this molecular chaperone. PU-20F induces the degradation of oncogenic Her2 tyrosine kinase. PU-20F blocks the growth of breast cancer cells. PU-20F can be used in breast cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-121706
• CAS No.: 422508-29-0
• Molecular Formula: C20H24FN5O4
• Molecular Weight: 417.44
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source