VUF-6884

Overview

VUF-6884 (Compound 7j) is a histamine receptor ( Histamine Receptor ) ligand with activity toward human H4R and H1R . Its pEC 50 and pK i values against human H4R are 7.70 and 7.55, respectively, while those against human H1R are 8.17 and 8.11, respectively. VUF-6884 competitively binds to the orthosteric binding site of human H4R to displace histamine, and exhibits inverse agonist activity at human H1R .

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > Histamine Receptor

Product Information

• Catalog No.: HY-124912
• CAS No.: 3455-10-5
• Molecular Formula: C18H18ClN3O
• Molecular Weight: 327.81
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source