PARP10-IN-1

Overview

PARP10-IN-1 is a PARP10 inhibitor with an IC 50 of 1.8 μM, 2.7 μM, and >10-fold selectivity over most PARP family members, excluding PARP7 and PARP16 .PARP10-IN-1 inhibits PARP10 -mediated mono-ADP-ribosylation, including auto-MARylation of PARP10 and MARylation of its protein targets.PARP10-IN-1 is membrane permeable and inhibits PARP10 -dependent MARylation in human embryonic kidney cells.PARP10-IN-1 can be used for the research of cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-125217
• CAS No.: 2286261-72-9
• Molecular Formula: C16H13F3N2O
• Molecular Weight: 306.28
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source