L-2286

Overview

L-2286 is an orally active PARP-1 inhibitor. L-2286 alleviates carotid artery remodeling, oxidative stress and inflammation in spontaneously hypertensive rats, protects neurons in the dorsal hippocampus, and reduces pyramidal cell loss and gliosis without affecting blood pressure. L-2286 can be used in research related to hypertension.

Application

Products | Products > Disease Areas > Hypertension | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > PARP | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-129599
• CAS No.: 684276-17-3
• Molecular Formula: C15H19N3OS
• Molecular Weight: 289.40
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source