JZ-4109

Overview

JZ-4109 is a β-Glucocerebrosidase ( GCase ) modulator with an IC 50 of 8 nM for wild-type recombinant GCase. JZ-4109 binds to an allosteric site at the GCase dimer interface, stabilizes wild-type and GCase N370S mutant GCase, induces GCase dimerization. JZ-4109 increases GCase protein abundance. JZ-4109 can be used for the research of Parkinson's diseas.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Glycosidase

Product Information

• Catalog No.: HY-131570
• CAS No.: 1997359-63-3
• Molecular Formula: C22H18N4
• Molecular Weight: 338.41
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source