MAO-B-IN-54

Overview

MAO-B-IN-54 is a selective, reversible and competitiv monoamine oxidase B ( MAOB ) inhibitor with a human IC 50 of 0.052 μM and a K i of 0.028 μM. MAO-B-IN-54 shows weak activity MAOA . MAO-B-IN-54 occupies both the entrance and substrate cavity of MAOB, forming hydrophobic and hydrogen bonding interactions. MAO-B-IN-54 inhibits Aβ aggregation and ROS production. MAO-B-IN-54 can be used for the research of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-131660
• CAS No.: 52688-60-5
• Molecular Formula: C14H17N3
• Molecular Weight: 227.31
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source