GSK-3484862 (GMP)

Overview

GSK-3484862 GMP is GSK-3484862 ( HY-135146 ) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1 . GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT , and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis , and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer , oral squamous cell carcinoma and lung adenocarcinoma.

Application

Products | Products > GMP Small Molecules | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > DNA Methyltransferase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-135146G
• CAS No.: 2170136-65-7
• Molecular Formula: C19H19N5OS
• Molecular Weight: 365.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source