Asulacrine isethionate

Overview

Asulacrine isethionate (CI-921 isethionate) is a derivative of Amsacrine ( HY-13551 ), a Topoisomerase II inhibitor and an anticancer agent. Asulacrine isethionate binds to DNA via intercalation, forming stable complexes with long residence times at DNA sites. Asulacrine isethionate mediates DNA breakage and DNA-protein cross-linking. Asulacrine isethionate exhibits anticancer activity against leukemia or lung cancer . Asulacrine isethionate can be used in research related to breast cancer , lung cancer , mouse solid tumors and leukemia.

Application

Products | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > DNA Alkylator/Crosslinker | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-13552
• CAS No.: 80841-48-1
• Molecular Formula: C26H30N4O8S2
• Molecular Weight: 590.67
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source