EGFR-IN-77

Overview

EGFR-IN-77 (Compound 4a) is a selective EGFR T790M/L858R inhibitor, with an IC 50 of 0.101 μM against EGFR T790M/L858R , 0.477 μM against EGFR L858R , and 1.771 μM against wild-type EGFR . EGFR-IN-77 exerts selective antiproliferative effects on EGFR T790M/L858R non-small cell lung cancer . EGFR-IN-77 can be used for the research of EGFR L858R/T790M double-mutant non-small cell lung cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-153605
• CAS No.: 2222930-49-4
• Molecular Formula: C26H28N6O3
• Molecular Weight: 472.54
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source