UBA6-IN-1 is a UBA6/UBE1L2 inhibitor ( IC 50 ≤50 nM) that acts by reducing the level of squalene epoxidase ( SQLE ). UBA6-IN-1 affects SREBP -dependent lipid metabolism processes and downstream cholesteryl ester transport, and can be used for cancer research.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CETP
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